Laboratory Manager

Laboratory Manager


Neogene Therapeutics is a pre-clinical stage biotechnology company aiming to change the paradigm of treatment for solid cancers. Our mission is to provide cancer patients with T cell therapies targeting mutated proteins called neo-antigens, which are present on cancer cells as a consequence of DNA mutations. Neogene is developing novel technologies to enable the engineering of ‘designer T cells’ with neo-antigen specificities that display an optimized ability to seek and destroy cancer cells.

For our R&D and our TCR discovery facilities located in Amsterdam, we are seeking a highly motivated individual for the role of Laboratory Manager to provide operational, technical, and administrative support through the management, planning, and allocation of resources. The R&D facility is responsible for development of our TCR discovery and T cell engineering platforms, while the personalized TCR discovery team is responsible for isolating neo-antigen specific TCRs from a cancer patient’s tumor biopsy & characterizing these tumor derived TCRs in a clinical laboratory setting. Following isolation and characterization, neo-antigen specific TCRs are selected and used for the manufacture of a fully personalized multi-specificity neo-antigen specific TCR engineered T cell therapy product that is used to treat the cancer patient. Reporting to the Vice President of R&D and the Director of the personalized TCR discovery team, the individual will assume responsibility for managing laboratory operations on a day-to-day basis.

Responsibilities include, but are not limited to:

  • Manage inventory, storage, restocking and usage of products using a cloud-based electronic laboratory notebook, guaranteeing resource availability and stock traceability in line with approved budgets.
  • Execute purchase orders using a designated procurement software, as well as evaluate and provide purchasing recommendations for laboratory reagents and supplies.
  • Alliance management with key suppliers, including initial contract discussions
  • Managing compliance of laboratory work in a formal quality management setting with applicable regulations set by appropriate accredited agencies, e.g., for genetically modified organisms (GMOs) and laboratory safety.
  • Support management and maintenance of inventory storage including cryogenic storage, usage of cell lines and clinical samples
  • Assist with developing and implementing new laboratory procedures and quality systems.
  • Run routine operational checks and/or calibrations on instruments, and schedule regular laboratory equipment maintenance services by vendors, ensuring thorough record-keeping of repairs and maintenance documentation.
  • Support laboratory setup and provide training during onboarding of new hires.
  • Other duties as assigned


  • Bachelor or Master’s in Biomedical Sciences or a related field with at least 5 years of relevant experience, including at least 3 years of experience in managing laboratory operations including clinical laboratory operations. Industry experience is preferred.
  • Knowledge on Dutch regulation on GMOs and laboratory safety is a must.
  • Candidates with experience of working within a formal quality management system is a strong plus
  • Working experience in cell culture, flow cytometry, DNA/RNA sequencing, PCR and/or other molecular biology techniques is a strong plus.
  • Experience of working in a regulated environment (e.g., cGMP or ISO 13485 production environment, ISO 15189 laboratory standards) is a plus
  • Comfortable with electronic document management systems and authoring tools.
  • Excellent organizational skills, a strong sense of urgency with regards to work duties and the ability to deliver results based on challenging timelines.
  • Strong verbal and written communication skills in English and Dutch.
  • Analytical and critical thinking, facilitating troubleshooting, decision making, and issue resolution.
  • Ability to manage and motivate a team in the context of laboratory operations duties. We are seeking a person who will lead the team by example and is a self-motivated team player with strong interpersonal skills.
  • Candidates must be authorized to work in The Netherlands.

We offer the opportunity to join a highly dynamic biotech start-up. You can expect a collaborative environment created by a team with deep scientific expertise and an industrial track-record in T cell therapies. We value pro-active team-players who pursue their goals with dedication, endurance and a daring mindset. If you share our commitment to make a difference to patients in need, we can provide an exciting opportunity for your career.

If you are interested, please submit your electronic application including cover letter and CV to

No recruiters. No phone calls.