Research Associate/Senior Research Associate, Process Development

Santa Monica

Neogene Therapeutics is a pre-clinical stage biotechnology company aiming to change the paradigm of treatment for solid cancers. Neogene is developing novel technologies to enable the engineering of ‘designer T cells’ with neo-antigen specificities that display an optimized ability to seek and destroy cancer cells.

We are seeking a highly motived, data-driven researcher to join our Process Development (PD) team as a Research Associate/Senior Research Associate. The successful candidate should have a knowledge of basic immunology principles, bioprocess development, and cGMP manufacturing. The candidate should also have experience in primary cell culture (T cells preferred), in different formats including flasks and bags. This role will support the development of a clinical manufacturing process of engineered T cells with patient-derived neo-antigen specific TCRs. The candidate will also be part of a team involved in implementing technology and participating in technology transfer to the clinical setting.

Responsibilities include, but are not limited to:

Execution of process development studies to develop, optimize, scale-up and transfer cGMP manufacturing processes
Perform cell culture of T cells in multiple formats including flasks, bags, and bioreactors
Collaborate within the project team to interpret study results and contribute to technical discussions for subsequent study design.
Prepare and review experimental proposals, technical reports, SOPs and manufacturing batch records.
Work collaboratively within PD group and cross-functionally with other groups to meat Tech Ops organization goals
Other responsibilities as assigned

Requirements:

MS degree in Immunology, Cell Biology, Molecular biology, Bioengineering, or relevant degrees with 1+ years relevant industry experience or BS degree with 2+ years relevant industry experience.
Experience in technical development of cell and gene therapy or biologics in early and late development setting
Hands-on experience in cell and gene therapy, specifically in T cells is highly desirable
Experience in Flow Cytometry his highly desired
Knowledge of cGMP manufacturing and regulations and practical experience in GMP operations is highly desirable
Knowledge of QbD, DOE and appropriate statistical analysis for process development
Ability to think critically, analytically and have demonstrated troubleshooting and problem-solving skills based on deductive reasoning

We offer the opportunity to join a highly dynamic growth-stage biotech company. You can expect a collaborative environment created by a team with deep scientific expertise and an industrial track-record in T cell therapies. We value proactive team-players who pursue their goals with dedication, endurance, and a daring mindset. If you share our commitment to make a difference to patients in need, we can provide a unique opportunity to be a major contributor to the success of a well-positioned, well-financed growth-stage biotechnology company.

If you are interested, please submit your electronic application including cover letter and CV to careers@neogene.com

No recruiters. No phone calls.

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Research Associate/Senior Research Associate, Process Development

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