Neogene Therapeutics is a pre-clinical stage biotechnology company aiming to change the paradigm of treatment for solid cancers. Our mission is to provide cancer patients with T cell therapies targeting mutated proteins called neo-antigens, which are present on cancer cells as a consequence of DNA mutations. Neogene is developing novel technologies to enable the engineering of ‘designer T cells’ with neo-antigen specificities that display an optimized ability to seek and destroy cancer cells.
We are seeking a highly motivated individual to join our personalized TCR Selection Team in Amsterdam as a (Senior) Research Associate – Molecular Biology and NGS. The personalized TCR Selection Team is responsible for applying Neogene Proprietary TCR selection platform, developed by our R&D team for the purpose of isolating neo-antigen specific TCRs from a cancer patient’s tumor biopsy & characterizing these tumor-derived TCRs. This process takes place in our personalized TCR Selection Facility under the principles of GLP. Following isolation and characterization, neo-antigen specific TCRs are selected for the clinical manufacture of a fully personalized multi-specificity neo-antigen specific TCR engineered T cell therapy product that is used to treat the patient. Reporting to a Senior Scientist in the personalized TCR selection team, the individual will assume responsibility for performing the process steps to isolate and characterize patient-derived neo-antigen specific TCRs for clinical use.
Responsibilities include, but are not limited to:
We offer the opportunity to join a highly dynamic biotech start-up. You can expect a collaborative environment created by a team with deep scientific expertise and an industrial track-record in T cell therapies. We value pro-active team-players who pursue their goals with dedication, endurance and a daring mindset. If you share our commitment to make a difference to patients in need, we can provide an exciting opportunity for your career.
If you are interested please submit your electronic application including cover letter and CV to firstname.lastname@example.org
No recruiters. No phone calls.