Director, Program Management

Santa Monica

Neogene Therapeutics is a pre-clinical stage biotechnology company aiming to change the treatment paradigm for solid cancers. Our mission is to provide cancer patients with T cell therapies targeting mutated proteins called neo-antigens, which are present on cancer cells as a consequence of DNA mutations. Neogene is developing novel technologies to enable the engineering of ‘designer T cells’ with neo-antigen specificities that display an optimized ability to seek and destroy cancer cells.

We are seeking a highly motivated and experienced Program Manager to build, manage and grow Neogene. This position will be located in Santa Monica, CA and directly reporting to the Vice President, Clinical Development in the U.S. This individual will have responsibility for the cross-functional planning and execution of one or more programs including definition of the cross functional operational strategy, management of timelines, cost, quality, and risk assessment and mitigation. The Program Manager provides an independent voice to shape the overall program and project strategy and drive optimal decisions for the broader portfolio value.

Responsibilities include, but are not limited to:

  • Accountable for creating and maintaining a cross-function development plan, timeline and budget for each program and ensuring progress.
  • Ensures all decisions are assessed as to their risks and impacts. Accountable for communication to team and stakeholders in a transparent and timely manner.
  • Proactively identifies risks and ensures mitigation plans are implemented
  • Accomplishes strategic objectives by overseeing multiple project activities.
  • Achieves operational objectives by contributing information and recommendations to strategic plans and reviews and preparing and completing action plans.
  • Facilitates the program strategy and timelines together with cross functional leads.
  • Leads scenario planning with clearly defined decision points.
  • Navigates the decision-making process with cross-functional teams
  • Ensures effective and efficient communication within and outside of the team.
  • Advises on governance expectations and prepares for key decision point discussions with focus on cross-functional input and rigorous debate.
  • Oversees and prepares program team budget including resources and costs, collaborating with Finance and other cross-functional departments.
  • Performs such other duties as may be assigned.


  • Bachelor’s degree in Life Sciences, Chemical Sciences, Physical sciences or other relevant discipline. Advanced degree preferred.
  • Minimum of 8 years of experience in biotech/pharmaceutical industry, preferably in the early development space.
  • Demonstrated competency in drug development expertise with solid understanding of disease area and drug development pathway with the ability to contribute to strategic discussions.
  • Leadership skills including situational leadership, ability to lead a team of experts and influence without authority.
  • Strong communicator able to integrate and succinctly summarize the various parts of a project and effectively tailor messages to audience including senior leadership.
  • Guides the preparation of high-quality documents and presentations for review at governance committees.
  • Ability to resolve complex problems and manage difficult stakeholder situations.
  • Ability to lead the development of critical path analyses and scenario planning.
  • Excellent project management skills – drives execution while balancing speed, quality, and cost.
  • Experience with commonly used project management tools including but not limited to Microsoft project.

We offer the opportunity to join a highly dynamic biotechnology company. You can expect a collaborative environment created by a team with deep scientific expertise and an industrial track-record in T cell therapies. We value pro-active team-players who pursue their goals with dedication, endurance and a daring mindset. If you share our commitment to make a difference to patients in need, we can provide a unique opportunity to be a major contributor to the success of a well-positioned, well-financed growth-stage biotechnology company

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